actemra dosing calculator
Actemra IV dosing in pJIA patients is calculated based on each patients weight as follows. To the volume of the ACTEMRA solution required for the patients dose.
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Actemra basics Actemra comes as a liquid solution.
. ACTEMRA SC can be used alone after steroids have been stopped. Figure C Check the liquid in the ACTEMRA prefilled syringe. Intravenous Dosing Regimen.
For patients 2 to less than 6 years old administer ORENCIA 15 mgkg as. Dosing information Usual Adult Dose of Actemra for Rheumatoid Arthritis. Patients less than 30 kg weight 12 mgkg Patients at or.
Hold dose then resume when platelet count 100000 cellsmm 3. Slowly add ACTEMRA for intravenous infusion from each vial into the infusion bag or bottle. Hold your ACTEMRA prefilled syringe with the covered needle pointing down See Figure C.
This dose can be taken through the prefilled syringe or ACTEMRA ACTPen autoinjector. ACTEMRA IV Dosing Childrens ACTEMRA doses are based on weight so your child will be weighed before every infusion appointment. Use alone or w methotrexate.
1 single 162-mg dose once a week in combination with a tapering steroid treatment. It can be given as an injection under your skin or as an intravenous IV infusion an injection into your vein given over time. Resume at 4 mgkg and increase to 8 mgkg as clinically appropriate.
If your childs weight changes you and your childs doctor may decide if a change of dose is necessary. The syringe is designed to deliver 162 mg per injection when used according to the instructions in. For patients 6 years and older administer ORENCIA 10 mgkg maximum dose of 1000 mg as an intravenous infusion over 60 minutes on the day before transplantation Day -1 followed by administration on Days 5 14 and 28 after transplantation.
Recommendations for dose interruptions in sJIA and pJIA patients can be found in Posology and Method of administration section 42 of the SmPC. Do not inject ACTEMRA if the liquid is cloudy discolored or has lumps or particles in it because it may not be safe to use. Your healthcare professional may decide to prescribe ACTEMRA SC once every other week based on their medical assessment.
4 mgkg IV as a 60-minute single drip infusion once every 4 weeks followed by an increase to 8 mgkg IV given once every 4 weeks as a 60-minute single drip infusion based on clinical response doses exceeding 800 mg per infusion are not recommended SUBCUTANEOUS. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to. It should be clear and colorless to pale yellow.
Patients weight in whole numbers lb. ACTEMRA IV Dosing and Administration Calculator Use this calculator as a guide to help determine your patients weight-based dose of ACTEMRA SJIA PJIA Rheumatoid Arthritis RA GCA Enter patient weight lb Recommended SJIA dosage every 2 weeks Patients Calculate Dose and Vial Combination CLEAR. For patients weighing Actemra dose For patients weighing 30 kg.
Actemra IV dosing in pJIA patients is calculated based on each patients weight as follows. The Weight-based medication dosing calculator is created by QxMD. ACTEMRA is a colorless to pale yellow liquid with a pH of about 65.
Actemra Tocilizumab is a biologic medicine that suppresses an overactive immune system in order to treat rheumatoid arthritis giant-cell arteritis and some types of juvenile arthritis. DOSAGE AND ADMINISTRATION Dose calculations for all indications and formulations IV can be found in the Actemra Dosing Guide as well as section 42 of the SmPC. Remember to discard any unused solution remaining in the single-use vials.
Patients weight kg x 8 mgkg Actemra dose Dosing Guide for Actemra tocilizumab IV for RA pJIA and sJIA April 2020 Version 602 6. 8 mgkgdose IV q2wk. RA or SSc-ILD IV.
Dosing Calculator for RA Treatment The recommended starting dose of ACTEMRA SC for patients 100 kg is 162 mg administered subcutaneously every week Page 4 of 13 ACTEMRA will be given to you by a healthcare professional using an intravenous line. Actemra works by blocking a receptor on the surface of cells thats related to the bodys immune response. The usual IV infusion dosing of Actemra for RA is 4 mg per kg given once every 4 weeks.
The interleukin-6 receptor IL-6R. Enter the patients weight in pounds or kilograms and click Calculate Dose The appropriate dose amount and number of single-use vials will appear. For example a person weighing 75 kg about 165 lb would receive 300 mg of Actemra once every 4 weeks.
Use the calculator below to determine the dose required for each patient. Important Side Effect Information Tears perforation of the Stomach or Intestines. Check whether a dosing adjustment is necessary.
162 mg SC q2wk. ACTEMRA is supplied as a sterile preservative-free solution for intravenous IV infusion at a concentration of 20 mg per mL. Use alone or w methotrexate.
See pkg insert for dose interruptions based on ASTALT ANC and Plt SC route 2 yo and older 30 kg Dose. The recommended dosage of ACTEMRA is a single 60-minute intravenous infusion as follows. To mix the solution gently invert the bag to avoid foaming.
For patients weighing Actemra dose For patients weighing 30 kg. Single-use vials are available containing 80 mg per 4 mL 200 mg per 10 mL or 400 mg per 20 mL of ACTEMRA.
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